Sapozhnikova M A
Arkh Patol. 1975;37(8):25-32.
Changes in 25 esophaguses following burns with cauterizing substances in patients treated with hormonal steroids and by bougienage were studied using histochemical methods. Effects of acids and alkalies were revealed at early stages of burn disease and consisted of lesions of a various depth of the esophagus wall. Formation of scars started from the first days after burns and led to the rearrangement of the esophagus wall. A year following the burn the healing of the damaged esophagus was not completed, and changes therein acquired a character of necrotic-ulcerative esophagitis. Hormonal treatment brought about a decrease in leucocytic infiltration in the esophagus wall. The periods of development of scars in the esophagus of patients treated with hormonal preparations according to the conventional scheme and treatment by bougienage coincided.
采用组织化学方法研究了25例因烧灼性物质烧伤食管的患者，这些患者接受了激素治疗并进行了探条扩张术。在烧伤疾病的早期阶段发现了酸和碱的作用，表现为食管壁不同深度的损伤。烧伤后第一天就开始形成瘢痕，导致食管壁结构重新排列。烧伤一年后，受损食管的愈合尚未完成，其变化呈现出坏死性溃疡性食管炎的特征。激素治疗使食管壁的白细胞浸润减少。按照传统方案接受激素制剂治疗的患者和接受探条扩张术治疗的患者，食管瘢痕形成的时期是一致的。
