Farrant P, Meire H B, Mieli-Vergani G
Department of Radiology, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
Br J Radiol. 2001 Oct;74(886):952-4. doi: 10.1259/bjr.74.886.740952.
Ultrasound scanning using a 13 MHz probe was performed on 158 infants, aged 12 weeks or less, presenting with conjugated hyperbilirubinaemia. The gall bladder was identified in 156 infants, 35 of whom had biliary atresia. The two patients in whom no gall bladder was seen both had biliary atresia. The gall bladder shape was normal in 128 patients (9 with biliary atresia) and irregular in 28 patients (26 with biliary atresia). The gall bladder wall was regular in 121 patients (4 with biliary atresia) and irregular in 35 patients (31 with biliary atresia). Combining these findings gave a sensitivity of 91.9%, a specificity of 96.7%, a positive predictive value of 89.5%, a negative predictive value of 97.5% and an accuracy rate of 95.6% for ultrasound of the gall bladder in the identification of biliary atresia. This compares with 90%, 92.4%, 75.3%, 97.3% and 91.9%, respectively, in our previous report using a 7 MHz probe.
对158名年龄在12周及以下、患有结合胆红素血症的婴儿进行了使用13兆赫探头的超声扫描。156名婴儿的胆囊被识别出来，其中35名患有胆道闭锁。未见到胆囊的两名患者均患有胆道闭锁。128名患者（9名患有胆道闭锁）的胆囊形状正常，28名患者（26名患有胆道闭锁）的胆囊形状不规则。121名患者（4名患有胆道闭锁）的胆囊壁规则，35名患者（31名患有胆道闭锁）的胆囊壁不规则。综合这些发现，胆囊超声在识别胆道闭锁方面的敏感性为91.9%，特异性为96.7%，阳性预测值为89.5%，阴性预测值为97.5%，准确率为95.6%。相比之下，我们之前使用7兆赫探头的报告中的相应数值分别为90%、92.4%、75.3%、97.3%和91.9%。
