Smythe H
Clin Orthop Relat Res. 1979 Sep(143):84-9.
The key to successful therapy for patients with ankylosing spondylitis is a lifelong, carefully devised, and well-instructed exercise program. This program is designed to maintain maximum range of motion within the spine, and the costovertebral and girdle joints, thereby preventing the tendency to flexion contractures and loss of height. The exercise program frequency requires long-term concomitant therapy with nonsteroidal anti-inflammatory drugs, partly to relieve the painful perispinal muscle spasm which frequently inhibits the exercise movements. The drugs are not known to alter the natural history of the inflammatory lesion. Local measures directed at ocular, urethral, and mucocutaneous inflammation may be symptomatically beneficial. These simple therapeutic principles ensure a good functional prognosis in the vast majority of patients with spondylitis.
强直性脊柱炎患者成功治疗的关键是制定一个终身的、精心设计且指导良好的锻炼计划。该计划旨在保持脊柱、肋椎关节和骨盆带关节的最大活动范围，从而防止出现屈曲挛缩倾向和身高降低。锻炼计划的实施频率需要与非甾体抗炎药长期联合治疗，部分原因是缓解经常抑制锻炼动作的脊柱周围肌肉疼痛性痉挛。目前尚不清楚这些药物会改变炎症病变的自然病程。针对眼部、尿道和皮肤黏膜炎症的局部治疗措施可能在症状上有益。这些简单的治疗原则可确保绝大多数脊柱炎患者获得良好的功能预后。
