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[天然实验制剂对假结核耶尔森菌吞噬作用免疫调节效果的比较研究]

[Comparative study of immunomodulating effects of natural experimental preparations on phagocytosis of Yersinia pseudotuberculosis].

作者信息

Dubrovina V I, Golubinskiĭ E P, Borsuk G I, Medvedeva S A, Aleksandrova G P, Konovalova Zh A, Semenov A A

出版信息

Med Parazitol (Mosk). 2001 Jul-Sep(3):44-6.

Abstract

To correct defects of the body's phagocytic system, the authors used experimental agents, such as vital activity products of plant cells, which were obtained by biotechnology. These included arabinogalactan, syringin, K-212, and DFEGP. The study agents activate the oxidative metabolism of macrophages, the production of active forms of oxygen, and thus enhance its bactericidal effect against Yersinia pseudotuberculosis. Syringin and arabinogalactan produce a more pronounced stimulating macrophageal effect in Yersinia pseudotuberculosis phagocytosis than do K-212 and DFEGP. The findings indicate that further studies of the effects of these tested and other agents on humoral and cellular immunity are required.

摘要

为纠正机体吞噬系统的缺陷,作者使用了实验制剂,如通过生物技术获得的植物细胞活性产物。这些产物包括阿拉伯半乳聚糖、紫丁香苷、K - 212和DFEGP。研究制剂可激活巨噬细胞的氧化代谢、活性氧的产生,从而增强其对假结核耶尔森菌的杀菌作用。在假结核耶尔森菌吞噬作用中,紫丁香苷和阿拉伯半乳聚糖比K - 212和DFEGP产生更明显的刺激巨噬细胞的效果。研究结果表明,需要进一步研究这些受试制剂及其他制剂对体液免疫和细胞免疫的影响。

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