Bellur S N
Neurology. 1975 Jun;25(6):502-7. doi: 10.1212/wnl.25.6.502.
Although the exact site of pathologic involvement and the pathogenesis remain uncertain, opsoclonus is an invaluable clinical sign that in it alone may herald an occult systemic malignancy. A thorough systematic evaluation should be undertaken to exclude an occult neoplasm in any patient who presents with opsoclonus unaccompanied by any other clinical sign.
尽管病理累及的确切部位和发病机制仍不明确,但眼阵挛是一种非常重要的临床体征,仅凭这一体征就可能预示着隐匿性全身恶性肿瘤。对于任何出现无其他临床体征伴随的眼阵挛的患者,都应进行全面系统的评估以排除隐匿性肿瘤。