Gay P E, Leaf R C, Arble F B
Pharmacol Biochem Behav. 1975 Jan-Feb;3(1):33-45. doi: 10.1016/0091-3057(75)90078-7.
Mouse-killing in rats was gradually inhibited by repeated posttest injections of d-amphetamine (1.5 mg/kg), l-amphetamine (1.5 mg/kg) or pilocarpine (7.5 mg/kg), but not by control substances. Of these drugs, only d-amphetamine inhibited killing when given prior to a mouse-killing test. Further experiments suggested that anorexia per se did not contribute to drug-induced inhibitory effects, but that changes in internal state were important to the development of inhibition. Pretest injections appear to inhibit predatory killing by a direct pharmacological action on some target site or sites, while posttest injections produce a learned aversion to predatory killing.
在杀鼠试验后重复注射右旋苯丙胺（1.5毫克/千克）、左旋苯丙胺（1.5毫克/千克）或毛果芸香碱（7.5毫克/千克）可逐渐抑制大鼠的杀鼠行为，但对照物质无此作用。在这些药物中，只有右旋苯丙胺在杀鼠试验前给药时可抑制杀鼠行为。进一步的实验表明，厌食本身并非药物诱导抑制作用的原因，而内部状态的改变对抑制作用的产生很重要。试验前注射似乎通过对某些靶位点的直接药理作用来抑制捕食性杀鼠行为，而试验后注射则产生对捕食性杀鼠行为的习得性厌恶。
