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低水平铅暴露对儿童发育的影响:中国近期研究

Impacts of low-level lead exposure on development of children: recent studies in China.

作者信息

Shen X, Wu S, Yan C

机构信息

Division of Environmental Sciences, Shanghai Institute for Pediatric Research, Xin Hua Hospital Affiliated to Shanghai Second Medical University, 1665 Kong Jiang Road, 200092, Shanghai, China.

出版信息

Clin Chim Acta. 2001 Nov;313(1-2):217-20. doi: 10.1016/s0009-8981(01)00675-1.

Abstract

BACKGROUND

In China, comprehensive epidemiological data relating to the prevalence of childhood lead poisoning are not available. However, existing data suggest that this disease may be widely pervasive as a result of rapid industrialization and the extensive use of leaded gasoline. About twenty publications have reported elevated blood lead levels (BPb) in children from different areas of the country. For the past 5 years, several prospective and retrospective studies have been added to evaluate the harmful health effects of lead at the current degrees of exposure in different places in China. The link between low-level lead exposure and deficits in IQ, neurobehavioral development and physical growth is remarkably consistent without exception.

CONCLUSIONS

The harmful health effects of childhood lead poisoning in limited studies of exposed and "unexposed" children demonstrate that this totally preventable disease warrants considerable public health attention in China.

摘要

背景

在中国,尚无关于儿童铅中毒患病率的全面流行病学数据。然而,现有数据表明,由于快速工业化和含铅汽油的广泛使用,这种疾病可能广泛存在。约有二十篇出版物报道了中国不同地区儿童血铅水平(BPb)升高的情况。在过去5年中,又增加了几项前瞻性和回顾性研究,以评估中国不同地区当前铅暴露程度下铅对健康的有害影响。低水平铅暴露与智商、神经行为发育和身体生长缺陷之间的联系无一例外都非常一致。

结论

在对暴露和“未暴露”儿童的有限研究中,儿童铅中毒对健康的有害影响表明,这种完全可预防的疾病在中国值得引起相当大的公共卫生关注。

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