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用于诊断囊性纤维化的汗液检测方法评估。

Assessment of sweat-testing practices for the diagnosis of cystic fibrosis.

作者信息

LeGrys V A

机构信息

Division of Clinical Laboratory Science, School of Medicine, University of North Carolina, Chapel Hill, NC 27599-7145, USA.

出版信息

Arch Pathol Lab Med. 2001 Nov;125(11):1420-4. doi: 10.5858/2001-125-1420-AOSTPF.

DOI:10.5858/2001-125-1420-AOSTPF
PMID:11697995
Abstract

OBJECTIVE

To describe the results of the College of American Pathologists survey questions assessing the current practice of sweat testing in North America and to identify areas in which improvement is needed.

DATA SOURCE

Results of the supplemental questions to the SW-B 2000 survey.

STUDY SELECTION

Supplemental questions were designed to assess variation in sweat collection, analysis, and interpretation.

DATA EXTRACTION

Extractions of the data were made based on the relevance of the data to the objectives of the review.

DATA SYNTHESIS

The majority of laboratories surveyed performed sweat testing according to the procedures described in the National Committee for Clinical Laboratory Standards' document. The study revealed that a number of laboratories have adopted poor practice standards and are potentially compromising patient care. Areas of concern include the number of laboratories performing few sweat tests per year, the persistence of unreliable methodology, misunderstanding of collection parameters, lack of patient education, and erroneous result reporting.

CONCLUSIONS

The study identified areas of concern toward which educational efforts can be directed. Such efforts include the development of a College of American Pathologists accreditation checklist for sweat testing and targeted responses in the sweat analysis participant summary report.

摘要

目的

描述美国病理学家学会关于评估北美当前汗液检测实践的调查问卷结果,并确定需要改进的领域。

数据来源

SW-B 2000调查问卷补充问题的结果。

研究选择

补充问题旨在评估汗液采集、分析和解读方面的差异。

数据提取

根据数据与综述目标的相关性进行数据提取。

数据综合

大多数接受调查的实验室按照美国国家临床实验室标准委员会文件中描述的程序进行汗液检测。研究表明,一些实验室采用了不良的实践标准,可能会损害患者护理。令人担忧的领域包括每年进行少量汗液检测的实验室数量、不可靠方法的持续存在、对采集参数的误解、缺乏患者教育以及错误的结果报告。

结论

该研究确定了可针对其开展教育工作的关注领域。这些工作包括制定美国病理学家学会汗液检测认可清单以及在汗液分析参与者总结报告中给出针对性回应。

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