D'Andrea G, Granella F, Ghiotto N, Nappi G
Headache and Comorbidity Center, Pathology Unit, Este-Monselice Hospital, Este, Italy.
Neurology. 2001 Nov 13;57(9):1723-5. doi: 10.1212/wnl.57.9.1723.
Short-lasting, unilateral, neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is considered an intractable condition. The authors treated five patients with lamotrigine (125 to 200 mg daily), obtaining a complete remission in three patients and a substantial reduction (about 80%) of attack frequency in the other two. No adverse effects were noted.