Piovesan Elcio Juliato, Siow Charles, Kowacs Pedro Andre, Werneck Lineu Cesar
Headache Unit, Neurology Division, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, PR, Brazil.
Arq Neuropsiquiatr. 2003 Sep;61(3A):691-4. doi: 10.1590/s0004-282x2003000400032. Epub 2003 Sep 16.
The SUNCT syndrome is characterized by a short-lasting headache in the first division of the trigeminal nerve, associated with ipsilateral autonomic symptoms. It is highly refractory to prophylactic medication. We describe a case where lamotrigine reduced the intensity, duration, and frequency of attacks and increased the remission period of this disorder. Over a two-year period, the attacks came back immediately whenever the patient reduced the dose or neglected treatment. We concluded that lamotrigine is effective in treating SUNCT syndrome when used in high doses for a prolonged period of time.
