MMWR Morb Mortal Wkly Rep. 2001 Nov 2;50(43):954-8.
Lower extremity amputation (LEA) is a costly and disabling procedure that disproportionately affects persons with diabetes. One of the national health objectives for 2000 was to reduce the LEA rate from a 1991 baseline of approximately eight per 1,000 persons with diabetes to a target of approximately five per 1,000 persons with diabetes. Review of 1996 data indicated an LEA rate of approximately 11. To estimate the national rates of hospital discharges for LEA among persons with and without diabetes and to assess the excess risk for LEA among persons with diabetes, CDC and the Agency for Healthcare Research and Quality (AHRQ) analyzed data from the 1997 Nationwide Inpatient Sample (NIS) and the 1997 National Health Interview Survey (NHIS). This report summarizes the findings of the analysis, which indicated that the age-adjusted rates of hospital discharges among persons with LEA who had diabetes were 28 times that of those without diabetes. This higher rate underscores the need to increase efforts to prevent risk factors (e.g., peripheral vascular disease, neuropathy, and infection) that result in LEA among persons with diabetes.
下肢截肢（LEA）是一种代价高昂且会导致残疾的手术，对糖尿病患者的影响尤为严重。2000年的一项国家卫生目标是将下肢截肢率从1991年每1000名糖尿病患者约8例的基线水平降至每1000名糖尿病患者约5例的目标水平。对1996年数据的审查显示下肢截肢率约为11例。为了估计糖尿病患者和非糖尿病患者中下肢截肢的全国住院率，并评估糖尿病患者下肢截肢的额外风险，美国疾病控制与预防中心（CDC）和医疗保健研究与质量局（AHRQ）分析了1997年全国住院患者样本（NIS）和1997年国家健康访谈调查（NHIS）的数据。本报告总结了分析结果，结果表明，患有糖尿病的下肢截肢患者的年龄调整后住院率是未患糖尿病患者的28倍。这一较高的比率凸显了加大力度预防导致糖尿病患者下肢截肢的风险因素（如外周血管疾病、神经病变和感染）的必要性。
