Nascimento A B, Mitchell D G, Zhang X M, Kamishima T, Parker L, Holland G A
Department of Radiology, Thomas Jefferson University Hospital, 132 S 10th St, Suite 1096, Main Bldg, Philadelphia, PA 19107, USA.
Radiology. 2001 Dec;221(3):628-32. doi: 10.1148/radiol.2213010178.
To establish age-based standards for renal cysts depicted at magnetic resonance (MR) imaging and to compare these standards with existing standards for ultrasonography (US).
Three radiologists reviewed subsecond T2-weighted single-shot fast spin-echo kidney MR imaging findings in 528 patients (248 men, 280 women) selected from consecutive abdominal MR studies without regard to clinical indication. Age, sex, and number and diameter of cysts were noted. Results were analyzed with nonparametric tests and were compared with published US results.
Men (mean, 2.0; 95% CI: 1.5, 2.5) had more renal cysts than women (mean, 1.2; 95% CI: 0.9, 1.5) (P < .001). Number and diameter of cysts increased with age (P < .001). Of 528 patients, 330 (62.5%) had at least one renal cyst, and 315 (59.7%) had cysts of 10 mm or less. MR imaging findings were comparable to published US criteria for type 1 autosomal dominant polycystic kidney disease (ADPKD) if only cysts larger than 1 cm were considered: Only one subject in the group of 18-29-year-old subjects had at least two renal cysts, and five of 493 subjects aged 30-59 years had at least two cysts in each kidney.
Compared with reported US results, MR imaging depicted an increased number of simple renal cysts in healthy individuals because of its increased sensitivity for cysts smaller than 1 cm. If only simple renal cysts larger than 1 cm are considered, US criteria for type 1 ADPKD can be applied to MR imaging.
建立基于年龄的磁共振成像（MR）所显示肾囊肿的标准，并将这些标准与现有的超声（US）标准进行比较。
三位放射科医生回顾了从连续腹部MR研究中选取的528例患者（248例男性，280例女性）的亚秒级T2加权单次激发快速自旋回波肾脏MR成像结果，选取时不考虑临床指征。记录年龄、性别以及囊肿的数量和直径。结果采用非参数检验进行分析，并与已发表的超声结果进行比较。
男性（平均2.0；95%可信区间：1.5，2.5）的肾囊肿比女性（平均1.2；95%可信区间：0.9，1.5）更多（P <.001）。囊肿的数量和直径随年龄增加（P <.001）。在528例患者中，330例（62.5%）至少有一个肾囊肿，315例（59.7%）有直径小于或等于10 mm的囊肿。如果仅考虑大于1 cm的囊肿，MR成像结果与已发表的1型常染色体显性多囊肾病（ADPKD）的超声标准相当：在18 - 29岁的受试者组中只有一名受试者至少有两个肾囊肿，在493例30 - 59岁的受试者中，有5例每个肾脏至少有两个囊肿。
与报道的超声结果相比，MR成像显示健康个体中单纯性肾囊肿的数量增加，因为其对小于1 cm的囊肿敏感性更高。如果仅考虑大于1 cm的单纯性肾囊肿，1型ADPKD的超声标准可应用于MR成像。
