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伴有急性皮质盲的溶血、肝酶升高和血小板减少(HELLP)综合征

Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome with acute cortical blindness.

作者信息

Tung C F, Peng Y C, Chen G H, Chow W K, Yang D Y, Hu W H

机构信息

Department of Emergency Medicine, Taichung Veterans General Hospital, Taiwan, ROC.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 2001 Aug;64(8):482-5.

PMID:11720149
Abstract

The coincidence of hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome and cortical blindness is an uncommon but very dramatic event. We describe a case of HELLP syndrome complicating with acute cortical blindness before delivery. A 27 year-old woman, gravida 1, para 0, with normal medical history, was referred to our emergency department at the 33th week of gestation due to headache, vomiting, and blurred vision. The ophthalmologic examination showed intact pupillary light reflexes and normal ophthalmoscopic findings, but no light perception in either eye. Brain computed tomography showed normal findings. HELLP syndrome and preeclampsia was diagnosed based on the findings of hypertension and proteinuria as well as laboratory data. Prompt delivery was performed in order to achieve good maternal and neonatal outcomes.

摘要

溶血、肝酶升高和血小板计数降低(HELLP)综合征与皮质盲同时出现是一种罕见但非常严重的情况。我们描述了一例在分娩前并发急性皮质盲的HELLP综合征病例。一名27岁初产妇,既往病史正常,在妊娠33周时因头痛、呕吐和视力模糊被转诊至我院急诊科。眼科检查显示瞳孔对光反射正常,眼底检查结果正常,但双眼均无光感。脑部计算机断层扫描显示结果正常。根据高血压、蛋白尿以及实验室检查结果诊断为HELLP综合征和子痫前期。为了获得良好的母婴结局,立即进行了分娩。

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引用本文的文献

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Saudi J Ophthalmol. 2013 Jan;27(1):51-3. doi: 10.1016/j.sjopt.2012.04.003. Epub 2012 Apr 23.
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Purtscher's retinopathy in pre-eclampsia: a blinding combination.先兆子痫中的普尔夏视网膜病变:一种致盲组合。
Int Ophthalmol. 2014 Feb;34(1):103-6. doi: 10.1007/s10792-013-9739-1. Epub 2013 Feb 15.