Chuh A A, Chiu S S, Peiris J S
Department of Medicine, University of Hong Kong, China.
Acta Derm Venereol. 2001 Aug-Sep;81(4):289-90. doi: 10.1080/00015550152572958.
An association between pityriasis rosea and human herpesvirus 7 (HHV-7) has been reported but remains controversial. The purpose of the present study was to investigate the association between HHV-6 and HHV-7 with pityriasis rosea. Fifteen patients aged 6-54 years with a diagnosis of pityriasis rosea and 15 age-matched controls were recruited. None of the patients had HHV-6 or HHV-7 DNA detected by polymerase chain reaction in the acute or convalescent plasma specimen. In the acute peripheral blood leucocytes specimen, 3 patients and one control had RHV-6 DNA detected (p=0.299; NS), while 7 patients and 5 controls had HHV-7 DNA (p=0.355; NS). Antibody to HHV-6 was detected in the acute specimen of 13 patients and 13 controls, while antibody to HHV-7 was found in all 15 of patients and controls. We thus found no evidence of recent HHV-6 or HHV-7 infection in patients with a diagnosis of pityriasis rosea.
已有报告称玫瑰糠疹与人类疱疹病毒7（HHV - 7）之间存在关联，但仍存在争议。本研究的目的是调查HHV - 6和HHV - 7与玫瑰糠疹之间的关联。招募了15名年龄在6至54岁之间诊断为玫瑰糠疹的患者和15名年龄匹配的对照。在急性或恢复期血浆样本中，通过聚合酶链反应未检测到任何患者的HHV - 6或HHV - 7 DNA。在急性外周血白细胞样本中，3名患者和1名对照检测到RHV - 6 DNA（p = 0.299；无统计学意义），而7名患者和5名对照检测到HHV - 7 DNA（p = 0.355；无统计学意义）。在13名患者和13名对照的急性样本中检测到HHV - 6抗体，而在所有15名患者和对照中均发现了HHV - 7抗体。因此，我们没有发现诊断为玫瑰糠疹的患者近期感染HHV - 6或HHV - 7的证据。
