Starkey R H, Cohen S, Orth D N
Science. 1975 Sep 5;189(4205):800-2. doi: 10.1126/science.1172293.
Epidermal growth factor is a polypeptide hormone that was previously identified only in mice. It causes proliferation and keratinization of epidermal tissues. An immune affinity column extraction technique was used to purify partially a substance from human urine which was similar to the mouse hormone in both its biological activity and immunoreactivity.
表皮生长因子是一种多肽激素，此前仅在小鼠中被鉴定出来。它能引起表皮组织的增殖和角化。采用免疫亲和柱提取技术从人尿中部分纯化出一种物质，该物质在生物活性和免疫反应性方面均与小鼠激素相似。
