与急性细小病毒B19和人疱疹病毒6型合并感染相关的致命性心肌炎。
Fatal myocarditis associated with acute parvovirus B19 and human herpesvirus 6 coinfection.
作者信息
Rohayem J, Dinger J, Fischer R, Klingel K, Kandolf R, Rethwilm A
机构信息
Institut für Virologie, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany.
出版信息
J Clin Microbiol. 2001 Dec;39(12):4585-7. doi: 10.1128/JCM.39.12.4585-4587.2001.
Abstract
We report on the case of a healthy young boy who developed a fulminant myocarditis due to acute coinfection with erythrovirus (parvovirus B19) and human herpesvirus 6 (HHV-6) in the absence of an antiviral immune response. We suggest that the HHV-6-induced immunosuppression enhanced dissemination of parvovirus B19, which led to fatal myocarditis.
摘要
我们报告了一例健康小男孩的病例，该患儿在缺乏抗病毒免疫反应的情况下，因同时急性感染细小病毒（B19型细小病毒）和人类疱疹病毒6型（HHV-6）而发生暴发性心肌炎。我们认为，HHV-6诱导的免疫抑制增强了B19型细小病毒的传播，从而导致致命性心肌炎。
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