• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

人类疱疹病毒6型（HHV-6）B亚型在美国婴儿群体中，是大多数有症状的原发性HHV-6感染的病原体。

Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants.

作者信息

Dewhurst S, McIntyre K, Schnabel K, Hall C B

机构信息

Department of Microbiology and Immunology, University of Rochester Medical Center, New York 14642.

出版信息

J Clin Microbiol. 1993 Feb;31(2):416-8. doi: 10.1128/jcm.31.2.416-418.1993.

DOI:10.1128/jcm.31.2.416-418.1993
PMID:8381815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC262777/
Abstract

Two variants of human herpesvirus 6 were identified. To assess their epidemiology and disease association, we analyzed viral isolates and/or uncultured peripheral blood mononuclear cells from 76 infants with symptomatic primary infection. In 97% of cases, human herpesvirus 6 variant B was detected, but variant A was not.

摘要

已鉴定出两种人类疱疹病毒6型变体。为评估它们的流行病学特征及与疾病的关联，我们分析了76例有症状原发性感染婴儿的病毒分离株和/或未培养的外周血单个核细胞。在97%的病例中检测到人类疱疹病毒6型B变体，但未检测到A变体。

相似文献

1
Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants.人类疱疹病毒6型（HHV-6）B亚型在美国婴儿群体中，是大多数有症状的原发性HHV-6感染的病原体。
J Clin Microbiol. 1993 Feb;31(2):416-8. doi: 10.1128/jcm.31.2.416-418.1993.
2
Direct sequence analysis of human herpesvirus 6 (HHV-6) sequences from infants and comparison of HHV-6 sequences from mother/infant pairs.对婴儿的人疱疹病毒6型（HHV-6）序列进行直接序列分析，并比较母婴对的HHV-6序列。
Clin Infect Dis. 1995 Oct;21(4):1017-9. doi: 10.1093/clinids/21.4.1017.
3
Coinfection with human herpesvirus 6 variants A and B in lung tissue.肺组织中人类疱疹病毒6型A和B变体的双重感染。
J Clin Microbiol. 1996 Apr;34(4):877-81. doi: 10.1128/jcm.34.4.877-881.1996.
4
Antigenic outline of HHV-6 variants from infants with febrile illness.
New Microbiol. 1994 Jul;17(3):243-8.
5
Human herpesvirus-6 infection in children. A prospective study of complications and reactivation.儿童人类疱疹病毒6型感染。并发症与再激活的前瞻性研究。
N Engl J Med. 1994 Aug 18;331(7):432-8. doi: 10.1056/NEJM199408183310703.
6
Human herpesvirus-7 (HHV-7).人类疱疹病毒7型（HHV - 7）
In Vivo. 1994 Jul-Aug;8(4):549-54.
7
Presence of human herpesvirus 6 variants A and B in saliva and peripheral blood mononuclear cells of healthy adults.健康成年人唾液和外周血单个核细胞中人类疱疹病毒6型A和B变体的存在情况。
J Clin Microbiol. 1996 Dec;34(12):3223-5. doi: 10.1128/jcm.34.12.3223-3225.1996.
8
Prevalence of human herpesvirus 6 variant A and B infections in bone marrow transplant recipients as determined by polymerase chain reaction and sequence-specific oligonucleotide probe hybridization.通过聚合酶链反应和序列特异性寡核苷酸探针杂交法测定骨髓移植受者中人类疱疹病毒6型A和B亚型感染的患病率。
J Clin Microbiol. 1993 Jun;31(6):1515-20. doi: 10.1128/jcm.31.6.1515-1520.1993.
9
Detection of human herpesvirus-6 DNA by polymerase chain reaction in serum or plasma.
J Med Virol. 1992 Sep;38(1):7-10. doi: 10.1002/jmv.1890380103.
10
Human herpesvirus 6 DNA in peripheral blood cells and saliva from immunocompetent individuals.免疫功能正常个体外周血细胞和唾液中的人疱疹病毒6型DNA
J Clin Microbiol. 1993 May;31(5):1262-7. doi: 10.1128/jcm.31.5.1262-1267.1993.

引用本文的文献

1
CD317 functions as a key antiviral factor in human herpesvirus 6 (HHV-6) infection.CD317在人类疱疹病毒6型（HHV-6）感染中作为关键抗病毒因子发挥作用。
J Virol. 2025 Jul 22;99(7):e0084125. doi: 10.1128/jvi.00841-25. Epub 2025 Jun 24.
2
High incidence and viral load of HHV-6A in a multi-centre kidney transplant cohort.多中心肾移植队列中HHV-6A的高发病率和病毒载量
Front Transplant. 2023 Jun 26;2:1188535. doi: 10.3389/frtra.2023.1188535. eCollection 2023.
3
The Eruptive Fevers at Sixes and Sevens.杂乱无章的发疹热

本文引用的文献

1
Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction.通过聚合酶催化的链式反应在体外特异性合成DNA。
Methods Enzymol. 1987;155:335-50. doi: 10.1016/0076-6879(87)55023-6.
2
Identification of human herpesvirus 6-specific DNA sequences in two patients with non-Hodgkin's lymphoma.两名非霍奇金淋巴瘤患者中人类疱疹病毒6特异性DNA序列的鉴定。
Leukemia. 1988 Aug;2(8):496-502.
3
Identification of human herpesvirus-6 as a causal agent for exanthem subitum.鉴定人疱疹病毒6型为幼儿急疹的病原体。
Open Access Emerg Med. 2024 Apr 24;16:101-105. doi: 10.2147/OAEM.S448246. eCollection 2024.
4
HHV-6 infections in hospitalized young children of Gabon.加蓬住院幼儿的 HHV-6 感染。
Infection. 2023 Dec;51(6):1759-1765. doi: 10.1007/s15010-023-02077-w. Epub 2023 Jul 27.
5
Epstein-Barr virus infection after adolescence and human herpesvirus 6A as risk factors for multiple sclerosis.青春期后 EBV 感染和 HHV-6A 是多发性硬化症的危险因素。
Eur J Neurol. 2021 Feb;28(2):579-586. doi: 10.1111/ene.14597. Epub 2020 Nov 22.
6
The role of herpesvirus 6A and 6B in multiple sclerosis and epilepsy.单纯疱疹病毒 6A 和 6B 在多发性硬化症和癫痫中的作用。
Scand J Immunol. 2020 Dec;92(6):e12984. doi: 10.1111/sji.12984. Epub 2020 Oct 23.
7
Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis.针对人类疱疹病毒 6A 的血清学应答增加与多发性硬化症的风险相关。
Front Immunol. 2019 Nov 26;10:2715. doi: 10.3389/fimmu.2019.02715. eCollection 2019.
8
DR7 encoded by human herpesvirus 6 promotes glioma development and progression.人类疱疹病毒6编码的DR7促进神经胶质瘤的发展和进展。
Cancer Manag Res. 2019 Mar 12;11:2109-2118. doi: 10.2147/CMAR.S179762. eCollection 2019.
9
Human Herpes Virus 6 (HHV-6)-associated Lymphadenitis: Pitfalls in Diagnosis in Benign and Malignant Settings.人类疱疹病毒 6 型（HHV-6）相关淋巴结炎：良性和恶性环境中诊断的陷阱。
Am J Surg Pathol. 2018 Oct;42(10):1402-1408. doi: 10.1097/PAS.0000000000001121.
10
Detection frequency of human herpesviruses-6A, -6B, and -7 genomic sequences in central nervous system DNA samples from post-mortem individuals with unspecified encephalopathy.患有未明确脑病的尸检个体中枢神经系统DNA样本中人类疱疹病毒6A、6B和7基因组序列的检测频率
J Neurovirol. 2016 Aug;22(4):488-97. doi: 10.1007/s13365-015-0417-0. Epub 2016 Jan 4.
Lancet. 1988 May 14;1(8594):1065-7. doi: 10.1016/s0140-6736(88)91893-4.
4
Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders.在淋巴增生性疾病患者中分离出一种新型病毒——人疱疹病毒6型（HBLV）。
Science. 1986 Oct 31;234(4776):596-601. doi: 10.1126/science.2876520.
5
Antibody prevalence to HBLV (human herpesvirus-6, HHV-6) and suggestive pathogenicity in the general population and in patients with immune deficiency syndromes.普通人群及免疫缺陷综合征患者中人类疱疹病毒6型（HHV-6）抗体的流行情况及潜在致病性。
J Virol Methods. 1988 Sep;21(1-4):125-31. doi: 10.1016/0166-0934(88)90059-6.
6
Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction.通过Southern印迹法和聚合酶链反应可以区分人类疱疹病毒6型毒株中的几个组。
J Clin Microbiol. 1991 Feb;29(2):367-72. doi: 10.1128/jcm.29.2.367-372.1991.
7
Genomic polymorphism, growth properties, and immunologic variations in human herpesvirus-6 isolates.人类疱疹病毒6型分离株的基因组多态性、生长特性及免疫学差异
Virology. 1991 Oct;184(2):545-52. doi: 10.1016/0042-6822(91)90424-a.
8
Phenotypic and genetic polymorphisms among human herpesvirus-6 isolates from North American infants.北美婴儿人疱疹病毒6型分离株的表型和基因多态性
Virology. 1992 Sep;190(1):490-3. doi: 10.1016/0042-6822(92)91240-u.
9
Primary human herpesvirus 6 infection in young children.幼儿原发性人疱疹病毒6型感染
N Engl J Med. 1992 May 28;326(22):1445-50. doi: 10.1056/NEJM199205283262201.
10
A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection.一种以疲劳、神经和免疫紊乱以及活跃的人类疱疹病毒6型感染为特征的慢性疾病。
Ann Intern Med. 1992 Jan 15;116(2):103-13. doi: 10.7326/0003-4819-116-2-103.