Wilson P W
Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Endocrinol Metab Clin North Am. 2001 Dec;30(4):857-81. doi: 10.1016/s0889-8529(05)70219-x.
Diabetes mellitus, especially type 2 diabetes, is a growing concern in America. Longitudinal trends show that obesity is more prevalent than in the past, and the incidence of type 2 diabetes is also increasing. Type 2 diabetes typically doubles the CHD risk in men and triples the risk in women. Intervening to control lipid levels and blood pressure has been shown to be especially helpful in preventing CHD, but the impact of better glycemic control on CHD risk is less convincing, especially in clinical trials. Revascularization studies in diabetics show that coronary bypass surgery is related to better outcomes than angioplasty procedures.
糖尿病,尤其是2型糖尿病,在美国正日益受到关注。纵向趋势表明,肥胖比过去更为普遍,2型糖尿病的发病率也在上升。2型糖尿病通常使男性患冠心病的风险加倍,使女性患冠心病的风险增至三倍。已证明干预控制血脂水平和血压对预防冠心病特别有帮助,但更好的血糖控制对冠心病风险的影响则不那么令人信服,尤其是在临床试验中。糖尿病患者的血管重建研究表明,冠状动脉搭桥手术比血管成形术的效果更好。