Braunstein-Bercovitz H, Rammsayer T, Gibbons H, Lubow R E
Department of Psychology, Tel Aviv University, Ramat Aviv 69978, Israel.
Schizophr Res. 2002 Jan 1;53(1-2):109-21. doi: 10.1016/s0920-9964(01)00166-9.
Latent inhibition (LI) is the phenomenon in which subjects who have repeatedly experienced an irrelevant stimulus perform more poorly on a new learning task with that stimulus than with a novel stimulus, presumably because of a decline in stimulus-specific attention. The present article reviews the literature on LI deficits in high-schizotypal normal subjects and schizophrenic patients. Although LI-deficits have been thought to be specific to these groups, evidence is presented that the effects may be related to the anxiety components of high-schizotypality and related pathologies.