Weber K, Eisman R, Higgins S, Morey L, Patty A, Tausek M, Zeng Z B
Department of Biological Sciences, University of Southern Maine, Portland, Maine 04104-9300, USA.
Genetics. 2001 Nov;159(3):1045-57. doi: 10.1093/genetics/159.3.1045.
Genetic effects on an index of wing shape on chromosome 2 of Drosophila melanogaster were mapped using isogenic recombinants with transposable element markers. At least 10 genes with small additive effects are dispersed evenly along the chromosome. Many interactions exist, with only small net effects in homozygous recombinants and little effect on phenotypic variance. Heterozygous chromosome segments show almost no dominance. Pleiotropic effects on leg shape are only minor. At first view, wing shape genes form a rather homogeneous class, but certain complexities remain unresolved.
利用带有转座元件标记的同基因重组体，对黑腹果蝇2号染色体上翅形指标的遗传效应进行了定位。至少有10个具有小加性效应的基因沿染色体均匀分布。存在许多相互作用，在纯合重组体中只有很小的净效应，对表型变异影响很小。杂合染色体片段几乎没有显性现象。对腿形的多效性效应很小。乍一看，翅形基因形成了一个相当同质的类别，但某些复杂性仍未得到解决。
