Norry Fabian M, Gomez Federico H
Departamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IEGEBA (CONICET-UBA), Buenos Aires, C-1428-EGA, Argentina
Departamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, IEGEBA (CONICET-UBA), Buenos Aires, C-1428-EGA, Argentina.
J Insect Sci. 2017 Jan 27;17(1). doi: 10.1093/jisesa/iew115. Print 2017 Jan.
In insects, some developmentally related traits are negatively correlated. Here, we mapped Quantitative Trait Loci (QTL) for traits of eye size and head capsule, in an intercontinental set of recombinant inbred lines (RILs) of Drosophila melanogaster Composite interval mapping identified QTL on all major chromosomes. Two negatively correlated traits (size of eyes and between-eyes distance) were influenced by one QTL that appeared to be antagonistic between the traits (QTL cytological range is 25F5-30A6), consistent with a negative genetic correlation between these traits of the head capsule. Comparisons of QTL across traits indicated a nonrandom distribution over the genome, with a considerable overlap between some QTL across traits. Developmentally-related traits were influenced by QTL in a pattern that is consistent both with 1) the sign of the genetic correlation between the traits and 2) a constraint in the micro-evolutionary differentiation in the traits.
在昆虫中，一些与发育相关的性状呈负相关。在此，我们在一组洲际黑腹果蝇重组自交系（RILs）中，对眼睛大小和头壳性状进行了数量性状基因座（QTL）定位。复合区间作图在所有主要染色体上均鉴定到了QTL。两个负相关性状（眼睛大小和两眼间距）受一个似乎在性状间起拮抗作用的QTL影响（QTL细胞学范围为25F5 - 30A6），这与头壳这些性状之间的负遗传相关性一致。跨性状的QTL比较表明其在基因组上呈非随机分布，一些跨性状的QTL之间存在相当大的重叠。与发育相关的性状受QTL影响的模式，既与1）性状间遗传相关性的符号，又与2）性状微进化分化中的一个限制相一致。
