Wang D, Li F, Jiang Z
Department of Analytical Chemistry, Shenyang Pharmaceutical University, China.
Planta Med. 2001 Nov;67(8):748-9. doi: 10.1055/s-2001-18343.
Psoralea corylifolia L. fruit extracts exhibited osteoblastic proliferation stimulating activity in UMR106 cell line cultured in vitro. The flavonoids of corylin and bavachin were isolated and identified as active principles by activity-guided fractionation. The results suggested that Psoralea corylifolia L. fruit extracts and corylin and bavachin might stimulate bone formation or have potential activity against osteoporosis.
补骨脂果实提取物在体外培养的UMR106细胞系中表现出刺激成骨细胞增殖的活性。通过活性导向分离法，分离并鉴定出补骨脂素和补骨脂二氢黄酮为活性成分。结果表明，补骨脂果实提取物以及补骨脂素和补骨脂二氢黄酮可能刺激骨形成或具有抗骨质疏松的潜在活性。
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