Leyendecker G, Hinckers K, Nocke W, Plotz E J
Arch Gynakol. 1975;218(1):47-64. doi: 10.1007/BF00672283.
LH, FSH, estradiol-17beta, progesterone, 20alpha-dihydroprogesterone, 17alpha-hydroxyprogesterone, delta4-androstenedione and testosterone are determined by radioimmunoassay in serum daily during 11 menstrual cycles. Three of them had to be considered as cycles with corpus luteum insufficiency on the basis of basal body temperature, length of the luteal phase and the pattern of progesterone concentration in serum. One woman conceived during the investigated cycle. The present concepts of the regulation of ovulation are discussed on the basis of the chronological relationshp of changing endocrine parameters in serum during the cycles. The analysis of the hormone concentrations in serum during the cycles with corpus luteum insufficiency supports the view that corpus luteum insufficiency could be caused by an insufficient stimulation of the growing follicle, but other ethiological factors have also to be considered.
在11个月经周期中，每天采用放射免疫分析法测定血清中的促黄体生成素（LH）、促卵泡生成素（FSH）、雌二醇-17β、孕酮、20α-二氢孕酮、17α-羟孕酮、Δ4-雄烯二酮和睾酮。根据基础体温、黄体期长度以及血清中孕酮浓度模式，其中3个周期被判定为黄体功能不全。1名女性在研究周期内受孕。根据周期中血清内分泌参数变化的时间关系，对当前的排卵调节概念进行了讨论。对黄体功能不全周期中血清激素浓度的分析支持了这样一种观点，即黄体功能不全可能是由于生长卵泡刺激不足所致，但也必须考虑其他病因因素。
