Luthra R, Nemesure B B, Wu S Y, Xie S H, Leske M C
Data Collection Center, Barabdos Eye Study, Bridgetown.
Arch Ophthalmol. 2001 Dec;119(12):1827-32. doi: 10.1001/archopht.119.12.1827.
To describe the distribution and risk factors for pterygium in the predominantly black population of the Barbados Eye Study, which was based on a random sample of Barbadian-born citizens between the ages of 40 and 84 years.
The standardized protocol included ophthalmic and other measurements, automated perimetry, lens gradings, fundus photography, and a detailed interview. A 10% systematic sample of participants and those meeting specific criteria also received a comprehensive ophthalmologic evaluation.
The Barbados Eye Study included 4709 participants, of whom 2978 were referred for an ophthalmologic evaluation and 2781 (93%) completed the examination. Cases of pterygium were found among 23.4% of 2617 black, 23.7% of 97 mixed (black and white), and 10.2% of 59 white participants examined. In addition to African ancestry, logistic regression analyses indicated a positive association between pterygium and age (odds ratio [OR], 1.01; 95% confidence interval [CI], 1.00-1.02), fewer years of education (OR, 1.43; 95% CI, 1.01-2.03), and an outdoor job location (OR, 1.87; 95% CI, 1.52-2.29). Having a darker skin complexion (OR, 0.66; 95% CI, 0.52-0.83), always using sunglasses outdoors (OR, 0.18; 95% CI, 0.06-0.59), and the use of prescription glasses (OR, 0.75; 95% CI, 0.60-0.93) were protective factors.
Approximately one quarter of the black participants examined had pterygia, a frequency that was 2.5 to 3 times higher than among whites in the Barbados Eye Study and elsewhere. Pterygium was almost twice as frequent among persons who worked outdoors but was only one fifth as likely among those who always used sunglasses outdoors. Educational interventions to modify these potential exposures may assist in preventing pterygium.
在巴巴多斯眼病研究中，以40至84岁出生于巴巴多斯的公民的随机样本为基础，描述主要为黑人的人群中翼状胬肉的分布情况及危险因素。
标准化方案包括眼科及其他测量、自动视野检查、晶状体分级、眼底照相及详细访谈。10%的参与者系统样本以及符合特定标准的参与者还接受了全面的眼科评估。
巴巴多斯眼病研究纳入了4709名参与者，其中2978人被转诊进行眼科评估，2781人（93%）完成了检查。在接受检查的2617名黑人参与者中，23.4%患有翼状胬肉；97名混血（黑人和白人）参与者中，23.7%患有翼状胬肉；59名白人参与者中，10.2%患有翼状胬肉。除非洲血统外，逻辑回归分析表明，翼状胬肉与年龄（比值比[OR]，(1.01)；95%置信区间[CI]，(1.00 - 1.02)）、受教育年限较少（OR，(1.43)；95% CI，(1.01 - 2.03)）以及户外工作地点（OR，(1.87)；95% CI，(1.52 - 2.29)）呈正相关。肤色较深（OR，(0.66)；95% CI，(0.52 - 0.83)）、在户外始终佩戴太阳镜（OR，(0.18)；95% CI，(0.06 - 0.59)）以及佩戴处方眼镜（OR，(0.75)；95% CI，(0.60 - 0.93)）是保护因素。
接受检查的黑人参与者中约四分之一患有翼状胬肉，这一频率比巴巴多斯眼病研究及其他地方的白人高出2.5至3倍。在户外工作的人中翼状胬肉的发病率几乎是其他人的两倍，但在户外始终佩戴太阳镜的人中发病率仅为五分之一。针对这些潜在暴露因素进行教育干预可能有助于预防翼状胬肉。
