Kaku T, Miyata T, Uruno T, Sako I, Kinoshita A
Arzneimittelforschung. 1975 Mar;25(3):343-7.
For the purpose of clarification of pharmacological actions of ginseng saponins we tried the isolation of ginseng saponins on a larger scale and succeeded in the isolation of eight saponins in a pure state and in sufficient amounts for the pharmacological assay. These eight saponins agreed all completely with the authentic samples of Shibata-Shoji and co-workers in molecular formula of saponins and sapogenins, sugars and TLC. The physical properties of saponins were shown. As other components of ginseng, there were isolated small amounts of panaxadiol, panaxatriol, daucosterol from the first running of column chromatography and mannitol, sucrose and glucose from the ethanol insoluble aqueous extract.
为了阐明人参皂苷的药理作用，我们尝试大规模分离人参皂苷，并成功分离出8种纯皂苷，其数量足以进行药理分析。这8种皂苷在皂苷、皂苷元、糖的分子式以及薄层层析方面与柴田承二及其同事的标准样品完全一致。文中展示了皂苷的物理性质。作为人参的其他成分，从柱色谱的第一次洗脱液中分离出了少量的人参二醇、人参三醇、胡萝卜苷，从乙醇不溶性水提取物中分离出了甘露醇、蔗糖和葡萄糖。
