通过（33）S核磁共振光谱法检测生物组织中的牛磺酸。

Detection of taurine in biological tissues by (33)S NMR spectroscopy.

作者信息

Musio R, Sciacovelli O

机构信息

Centro C.N.R. di Studio sulle Metodologie Innovative di Sintesi Organiche, Dipartimento di Chimica, Università degli Studi di Bari, Via E. Orabona 4, Bari, 70126, Italy.

出版信息

J Magn Reson. 2001 Dec;153(2):259-61. doi: 10.1006/jmre.2001.2437.

DOI:10.1006/jmre.2001.2437

PMID:11740903

Abstract

The potential of (33)S NMR spectroscopy for biochemical investigations on taurine (2-aminoethanesulfonic acid) is explored. It is demonstrated that (33)S NMR spectroscopy allows the selective and unequivocal identification of taurine in biological samples. (33)S NMR spectra of homogenated and intact tissues are reported for the first time, together with the spectrum of a living mollusc. Emphasis is placed on the importance of choosing appropriate signal processing methods to improve the quality of the (33)S NMR spectra of biological tissues.

摘要

探讨了³³S核磁共振光谱在牛磺酸（2-氨基乙磺酸）生化研究中的潜力。结果表明，³³S核磁共振光谱能够对生物样品中的牛磺酸进行选择性且明确的鉴定。首次报道了匀浆组织和完整组织的³³S核磁共振谱，以及活体软体动物的谱图。重点强调了选择合适的信号处理方法以提高生物组织³³S核磁共振谱质量的重要性。