Hewson J R, Holland A J
Can Anaesth Soc J. 1975 Sep;22(5):539-46. doi: 10.1007/BF03013406.
In this initial study, it has been postulated that even the simple bronchial administration of isotonic glucose and insulin can maintain alveolar cell metabolism as measured by A.T.P. activity; further studies, using aerosolized glucose solutions, will test the validity of the hypothesis that alveolar metabolism can be maintained by the administration of substrate in aerosolized form by the alveolar route and will determine whether this form of substrate administration has clinical potential.
在这项初步研究中,有人提出,即使是通过支气管简单给予等渗葡萄糖和胰岛素,也能维持以三磷酸腺苷(ATP)活性衡量的肺泡细胞代谢;使用雾化葡萄糖溶液的进一步研究,将检验通过肺泡途径给予雾化形式的底物可维持肺泡代谢这一假说的有效性,并将确定这种底物给药形式是否具有临床潜力。