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钕钇铝石榴石可视化激光前列腺切除术:230例患者的7年经验

Neodymium:YAG visual laser ablation of the prostate: 7 years of experience with 230 patients.

作者信息

Sengör Feridun, Gürdal Mesut, Tekin Ali, Yücebaş Ergin, Beysel Melih, Erdoğan Kubilay

机构信息

Department of Urology, Haydarpaå Numune Education and Research Hospital, Istanbul, Turkey.

出版信息

J Urol. 2002 Jan;167(1):184-7. doi: 10.1016/s0022-5347(05)65408-0.

Abstract

PURPOSE

We evaluated the short and long-term outcome of neodymium:YAG visual laser ablation prostatectomy for treatment of benign prostatic hyperplasia (BPH).

MATERIALS AND METHODS

A total of 230 patients with symptomatic BPH underwent visual laser ablation prostatectomy. Evaluation measures included the American Urological Association symptom score, maximum urinary flow rate, post-void residual urine volume and morbidity.

RESULTS

Median followup was 36 months (range 6 to 79). Of the patients 220, 196, 180, and 167 were available at 6 months, 1, 2 and 3 years, respectively. Moreover, 98 patients were followed for a minimum 5 years. At 6 months maximum urinary flow rate increased from 6.7 to 17.9 ml. per second, post-void residual urine volume decreased from 159 to 52 ml. and the American Urological Association symptom score was reduced from 22 to 7.2. Improvement in the evaluation parameters also continued at 5 years. Early complications consisted of prostatitis, urinary retention, and bleeding in 6 (2.6%), 3 (1.4%) and 1 (0.4%) patient, respectively. Irritative symptoms persisting greater than 4 weeks were seen in 28 (12.2%) patients. Late complications were bladder neck contracture, urethral stricture, and urinary retention in 3 (1.4%), 2 (0.9%) and 2 (0.9%) patients, respectively. Of the 153 sexually active men 5 noticed erectile impotence at 6 months. There were 20 (12.0%) patients who reported retrograde ejaculation. The reoperation rate was 5.5%.

CONCLUSIONS

Our results further confirmed that visual laser ablation prostatectomy is a safe and effective treatment for BPH. It has minimal morbidity and durable therapeutic effects. However, the major disadvantage is postoperative irritative voiding symptoms.

摘要

目的

我们评估了钕钇铝石榴石可视激光前列腺切除术治疗良性前列腺增生(BPH)的短期和长期疗效。

材料与方法

共有230例有症状的BPH患者接受了可视激光前列腺切除术。评估指标包括美国泌尿外科学会症状评分、最大尿流率、排尿后残余尿量和发病率。

结果

中位随访时间为36个月(范围6至79个月)。分别有220例、196例、180例和167例患者在6个月、1年、2年和3年时可进行评估。此外,98例患者至少随访了5年。6个月时,最大尿流率从6.7毫升/秒增加到17.9毫升/秒,排尿后残余尿量从159毫升减少到52毫升,美国泌尿外科学会症状评分从22分降至7.2分。评估参数在5年时也持续改善。早期并发症包括前列腺炎、尿潴留和出血,分别发生在6例(2.6%)、3例(1.4%)和1例(0.4%)患者中。28例(12.2%)患者出现持续超过4周的刺激性症状。晚期并发症分别为膀胱颈挛缩、尿道狭窄和尿潴留,各有3例(1.4%)、2例(0.9%)和2例(0.9%)患者。在153例有性生活的男性中,5例在6个月时出现勃起功能障碍。有20例(12.0%)患者报告有逆行射精。再次手术率为5.5%。

结论

我们的结果进一步证实可视激光前列腺切除术是治疗BPH的一种安全有效的方法。它发病率极低且治疗效果持久。然而,主要缺点是术后刺激性排尿症状。

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