Sorvillo F, Smith L, Kerndt P, Ash L
Department of Epidemiology, School of Public Health, University of California, Los Angeles, 90024, USA.
Emerg Infect Dis. 2001 Nov-Dec;7(6):927-32. doi: 10.3201/eid0706.010603.
Trichomonas vaginalis may be emerging as one of the most important cofactors in amplifying HIV transmission, particularly in African-American communities of the United States. In a person co-infected with HIV, the pathology induced by T. vaginalis infection can increase HIV shedding. Trichomonas infection may also act to expand the portal of entry for HIV in an HIV-negative person. Studies from Africa have suggested that T. vaginalis infection may increase the rate of HIV transmission by approximately twofold. Available data indicate that T. vaginalis is highly prevalent among African-Americans in major urban centers of the United States and is often the most common sexually transmitted infection in black women. Even if T. vaginalis increases the risk of HIV transmission by a small amount, this could translate into an important amplifying effect since Trichomonas is so common. Substantial HIV transmission may be attributable to T. vaginalis in African-American communities of the United States.
阴道毛滴虫可能正成为加剧艾滋病毒传播的最重要辅助因素之一，尤其是在美国非裔社区。在同时感染艾滋病毒的人中，阴道毛滴虫感染诱发的病理状况会增加艾滋病毒的脱落。滴虫感染在艾滋病毒阴性者中也可能起到扩大艾滋病毒进入途径的作用。非洲的研究表明，阴道毛滴虫感染可能使艾滋病毒传播率提高约两倍。现有数据表明，在美国主要城市中心的非裔美国人中，阴道毛滴虫感染非常普遍，而且往往是黑人女性中最常见的性传播感染。即使阴道毛滴虫仅小幅增加艾滋病毒传播风险，鉴于滴虫感染如此普遍，这也可能转化为重要的加剧效应。在美国非裔社区，大量的艾滋病毒传播可能归因于阴道毛滴虫。
