Macdonald J B
Br Med J. 1975 Sep 27;3(5986):753-5. doi: 10.1136/bmj.3.5986.753.
An analysis of 255 fibreoptic bronchoscopies showed that the major indication for bronchoscopy was suspected bronchial carcinoma (93% of cases). Of the 183 patients finally shown to have bronchial carcinoma 83% had abnormal bronchoscopy findings and 65% had bronchial biopsy specimens diagnostic of malignancy. These figures were superior to those obtainable with rigid bronchoscopy, particularly with upper lobe and peripheral tumours. Brush biopsy and bronchography were useful supplementary techniques. Sputum cytology gave poorer results than fibreoptic bronchoscopy, but enabled diagnosis in some otherwise undiagnosed cases. The complication rate was low and the claim of this new technique to be the investigation of choice in bronchial carcinoma seemed to be justified in clinical practice.
对255例纤维支气管镜检查的分析表明，支气管镜检查的主要指征是疑似支气管癌（占病例的93%）。在最终确诊为支气管癌的183例患者中，83%的患者支气管镜检查结果异常，65%的患者支气管活检标本诊断为恶性肿瘤。这些数据优于硬支气管镜检查所能获得的数据，尤其是对于上叶和周围型肿瘤。刷检活检和支气管造影是有用的辅助技术。痰细胞学检查的结果比纤维支气管镜检查差，但在一些其他方法无法确诊的病例中能够实现诊断。并发症发生率较低，这项新技术作为支气管癌首选检查方法的说法在临床实践中似乎是合理的。
