脑脊液流出阻力的颅内压依赖性：一种用于计算H-TX大鼠模型中脑脊液参数的新数学方法。
The ICP-dependency of resistance to cerebrospinal fluid outflow: a new mathematical method for CSF-parameter calculation in a model with H-TX rats.
作者信息
Meier U, Kiefer M, Bartels P
机构信息
Department of Neurosurgery, Unfallkrankenhaus Berlin, Germany.
出版信息
J Clin Neurosci. 2002 Jan;9(1):58-63. doi: 10.1054/jocn.2001.0930.
The international The simultaneous measurement of the resistance and compliance during a single investigation minimizes the patients exertion. In contrast to the classical method it is not necessary that the ICP reaches a plateau. Our mathematical method diverges with t he description of a pressure dependent slope of the function for the resistance from the static examination models. We proved our mathematical method by the use of a dynamic infusion test in 10 H-Tx rats without hydrocephalus and five hydrocephalic H-Tx rats. For that we are able to take the non linearity of the CSF resorption into consideration.
在单次检查中同时测量阻力和顺应性可将患者的用力程度降至最低。与传统方法不同，颅内压（ICP）无需达到平稳状态。我们的数学方法与静态检查模型中关于阻力函数压力依赖性斜率的描述有所不同。我们通过对10只无脑积水的H-Tx大鼠和5只脑积水H-Tx大鼠进行动态灌注试验，验证了我们的数学方法。通过这种方法，我们能够考虑脑脊液吸收的非线性。
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