Lipshultz S E, Fisher S D, Lai W W, Miller T L
Division of Pediatric Cardiology, University of Rochester Medical Center and Strong Children's Hospital, New York 14642, USA.
Ann N Y Acad Sci. 2001 Nov;946:236-73. doi: 10.1111/j.1749-6632.2001.tb03916.x.
Cardiovascular complications are important contributors to morbidity and mortality in HIV-infected patients. These complications can usually be detected at subclinical levels with monitoring, which can help guide targeted interventions. This article reviews available data on types and frequency of cardiovascular manifestations in HIV+ patients and proposes monitoring strategies aimed at early subclinical detection. In particular, we recommend routine echocardiography for HIV+ patients, even those with no evidence of cardiovascular disease. We also review preventive and therapeutic cardiovascular interventions. For procedures that have not been studied in HIV+ patients, we extrapolate from evidence-based guidelines for the general population.
心血管并发症是导致HIV感染患者发病和死亡的重要因素。通过监测,这些并发症通常可以在亚临床水平被检测到,这有助于指导针对性干预措施。本文综述了关于HIV阳性患者心血管表现类型和频率的现有数据,并提出了旨在早期亚临床检测的监测策略。特别是,我们建议对HIV阳性患者进行常规超声心动图检查,即使是那些没有心血管疾病证据的患者。我们还综述了心血管疾病的预防和治疗干预措施。对于尚未在HIV阳性患者中进行研究的治疗方法,我们根据针对普通人群的循证指南进行推断。