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HIV感染患者的心血管危险因素、监测与治疗

Cardiovascular risk factors, monitoring, and therapy for HIV-infected patients.

作者信息

Lipshultz Steven E, Fisher Stacy D, Lai Wyman W, Miller Tracie L

机构信息

Division of Pediatric Cardiology, University of Rochester Medical Center and Golisano Children's Hospital at Strong 14642, USA.

出版信息

AIDS. 2003 Apr;17 Suppl 1:S96-122. doi: 10.1097/00002030-200304001-00014.

DOI:10.1097/00002030-200304001-00014
PMID:12870537
Abstract

Cardiovascular complications are important contributors to morbidity and mortality in HIV-infected patients. These complications can usually be detected at subclinical levels with monitoring, which can help guide targeted interventions. This article reviews available data on types and frequency of cardiovascular manifestations in HIV-infected patients and proposes monitoring strategies aimed at early subclinical detection. In particular, we recommend routine echocardiography for HIV-infected patients, even those with no evidence of cardiovascular disease. We also review preventive and therapeutic cardiovascular interventions. For procedures that have not been studied in HIV-infected patients, we extrapolate from evidence-based guidelines for the general population.

摘要

心血管并发症是导致HIV感染患者发病和死亡的重要因素。通过监测,这些并发症通常可在亚临床水平被检测到,这有助于指导针对性干预措施。本文综述了关于HIV感染患者心血管表现的类型和发生率的现有数据,并提出了旨在早期亚临床检测的监测策略。特别是,我们建议对HIV感染患者,即使是那些没有心血管疾病证据的患者,进行常规超声心动图检查。我们还综述了心血管疾病的预防和治疗干预措施。对于尚未在HIV感染患者中进行研究的治疗方法,我们从基于循证的一般人群指南中进行推断。

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