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关于HIV感染患者代谢紊乱与心血管风险的共识文件执行摘要。

Executive summary of the consensus document on metabolic disorders and cardiovascular risk in patients with HIV infection.

机构信息

Secretaría del Plan Nacional sobre el Sida, Ministerio de Sanidad, Servicios Sociales e Igualdad, Madrid, España.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2019 Jan;37(1):50-55. doi: 10.1016/j.eimc.2017.06.007. Epub 2017 Aug 17.

Abstract

Patients with HIV infection have a higher cardiovascular risk than the general population. The identification of patients with high CVR, the implementation of preventive measures and the control of modifiable risk factors, especially in patients on antiretroviral therapy should be part of the management of HIV infection. This document updates the recommendations published in 2014, mainly regarding lipid, glucose, arterial hypertension alterations and cardiovascular risk (CVR). The objective of metabolic monitoring is A1C ≤7%, similar to that of non-infected population, individualising by age, life expectancy, comorbidities, hypoglycaemia risk and costs. Cardiovascular risk should be calculated in all HIV patients with a risk calculator available for clinical use, even though we recommend the use of REGICOR tables as we are treating the Spanish population. Proper measurement of blood pressure should be a routine practice in the care of patients with HIV infection. The aim of this document is to provide tools for the diagnosis and appropriate treatment of the main metabolic alterations to serve as a reference to professionals who care for people with HIV infection.

摘要

感染艾滋病毒的患者比普通人群有更高的心血管疾病风险。识别心血管疾病风险高的患者、实施预防措施以及控制可改变的风险因素,尤其是接受抗逆转录病毒治疗的患者,应成为艾滋病毒感染管理的一部分。本文件更新了2014年发布的建议,主要涉及脂质、血糖、动脉高血压改变和心血管疾病风险(CVR)。代谢监测的目标是糖化血红蛋白(A1C)≤7%,与未感染人群相似,并根据年龄、预期寿命、合并症、低血糖风险和成本进行个体化调整。所有艾滋病毒患者都应使用临床可用的风险计算器来计算心血管疾病风险,尽管由于我们治疗的是西班牙人群,我们建议使用REGICOR表格。在艾滋病毒感染患者的护理中,正确测量血压应成为常规操作。本文件的目的是提供诊断和适当治疗主要代谢改变的工具,以供护理艾滋病毒感染者的专业人员参考。

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