Ascher E, Hingorani A, Yorkovich W, Ramsey P J, Salles-Cunha S
Division of Vascular Surgery, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, N York 11219, USA.
Ann Vasc Surg. 2001 Nov;15(6):669-78. doi: 10.1007/s10016-001-0088-6.
It has been reported that carotid screening may be cost-effective in patient populations in which the prevalence of severe carotid stenosis exceeds 4.5%. In order to identify potential patient populations who might benefit from carotid screening, we examined the results of preoperative duplex scanning in patients undergoing open heart surgery. Between January 1995 and July 1998, 3708 patients (59% male, 41% female) underwent open heart surgery at our institution. Of these, 3081 underwent coronary artery bypass grafting (CABG), 364 underwent valve replacement (VR), and 263 underwent CABG and VR. The ages of these patients ranged from 40 years to 98 years (mean 68 +/- 11 years). The risk factors analyzed included hypertension (HTN), 59%; smoking (Smk), 53%; and diabetes (DM), 33%. Patients were divided into three groups according to their age. Group A consisted of the 835 patients who were < or = 60 years old, group B consisted of 2474 patients ranging from 61 years to 80 years old, and group C consisted of 399 patients who were > or = 81 years old. All patients underwent bilateral preoperative carotid duplex scans at an Intersocietal Commission for the Accreditation of Vascular Laboratories (ICAVL)-accredited vascular laboratory. Statistical analyses were performed using chi-squared, Fisher's exact test, linear regression, and multivariate analysis. From our results we concluded that carotid screening is not recommended for patients under 60 years of age who are undergoing CABG unless they present with a minimum of two of the following major risk factors: hypertension, diabetes, or smoking. However, carotid screening is recommended for all patients undergoing open heart operations who are over the age of 60 years old, regardless of the absence of associated risk factors.
据报道,在重度颈动脉狭窄患病率超过4.5%的患者群体中,颈动脉筛查可能具有成本效益。为了确定可能从颈动脉筛查中获益的潜在患者群体,我们检查了接受心脏直视手术患者的术前双功扫描结果。1995年1月至1998年7月期间,3708例患者(男性59%,女性41%)在我们机构接受了心脏直视手术。其中,3081例行冠状动脉旁路移植术(CABG),364例行瓣膜置换术(VR),263例行CABG和VR。这些患者的年龄在40岁至98岁之间(平均68±11岁)。分析的危险因素包括高血压(HTN),59%;吸烟(Smk),53%;糖尿病(DM),33%。患者根据年龄分为三组。A组由835例年龄≤60岁的患者组成,B组由2474例年龄在61岁至80岁之间的患者组成,C组由399例年龄≥81岁的患者组成。所有患者均在经血管实验室认证协会(ICAVL)认证的血管实验室进行了术前双侧颈动脉双功扫描。使用卡方检验、Fisher精确检验、线性回归和多变量分析进行统计分析。根据我们的结果,我们得出结论,对于接受CABG的60岁以下患者,除非他们至少存在以下两种主要危险因素:高血压、糖尿病或吸烟,否则不建议进行颈动脉筛查。然而,对于所有60岁以上接受心脏直视手术的患者,无论是否存在相关危险因素,均建议进行颈动脉筛查。