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马来西亚一家三级医院冠心病患者颅外颈动脉粥样硬化的患病率

Prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease in a tertiary hospital in Malaysia.

作者信息

Sahadevan Mahavishnu, Chee Kok Han, Tai Mei-Ling Sharon

机构信息

Division of Cardiology.

Division of Neurology, Department of Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.

出版信息

Medicine (Baltimore). 2019 Apr;98(15):e15082. doi: 10.1097/MD.0000000000015082.

Abstract

There is limited information regarding the prevalence of extracranial carotid atherosclerosis in the patients with coronary artery disease (CAD) undergoing coronary artery bypass graft (CABG) surgery in South East Asia. The primary objective was to assess the prevalence of extracranial carotid stenosis, raised carotid intima media thickness (CIMT), and plaques in the patients with CAD undergoing elective CABG. The secondary objective was to evaluate the risk factors for extracranial carotid atherosclerosis.A total of 119 consecutive patients with CAD undergoing elective CABG in a tertiary hospital in Malaysia were recruited. Data on the demographic characteristics and risk factors were collected. The ultrasound carotid Doppler findings comprising of raised CIMT, plaques, and stenosis in the extracranial carotid vessels were recorded.The mean age of the patients was 64.26 ± 10.12 (range 42-89). Most of the patients were men (73.1%). The patients consisted of 44 (37%) Malays, 26 (21.8%) Chinese, and 49 (41.2%) Indians.A total of 67 (56.3%) patients had raised CIMT, 89 (74.8%) patients had plaques, and 10 (8.4%) patients had stenosis in the internal and common carotid arteries. The mean age of patients with plaques was higher compared to those without plaques (66.00 ± 9.63 vs 59.10 ± 9.92, P = .001). The body mass index (BMI) of patients with stenosis was higher compared to those without stenosis (28.35 ± 4.92 vs 25.75 ± 3.16, P = .02).The patients with plaques were more likely to be older, whereas the patients with carotid stenosis were more likely to have higher BMI.

摘要

关于东南亚地区接受冠状动脉旁路移植术(CABG)的冠心病(CAD)患者颅外颈动脉粥样硬化的患病率,相关信息有限。主要目的是评估接受择期CABG的CAD患者颅外颈动脉狭窄、颈动脉内膜中层厚度(CIMT)升高和斑块的患病率。次要目的是评估颅外颈动脉粥样硬化的危险因素。

在马来西亚一家三级医院,共招募了119例连续接受择期CABG的CAD患者。收集了人口统计学特征和危险因素的数据。记录了超声颈动脉多普勒检查结果,包括颅外颈动脉血管的CIMT升高、斑块和狭窄情况。

患者的平均年龄为64.26±10.12岁(范围42 - 89岁)。大多数患者为男性(73.1%)。患者包括44名(37%)马来人、26名(21.8%)华人以及49名(41.2%)印度人。

共有67名(56.3%)患者CIMT升高,89名(74.8%)患者有斑块,10名(8.4%)患者颈内动脉和颈总动脉有狭窄。有斑块的患者平均年龄高于无斑块的患者(66.00±9.63 vs 59.10±9.92,P = 0.001)。有狭窄的患者体重指数(BMI)高于无狭窄的患者(28.35±4.92 vs 25.75±3.16,P = 0.02)。

有斑块的患者更可能年龄较大,而有颈动脉狭窄的患者更可能BMI较高。

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