Quirin R, Rasolofo V, Andriambololona R, Ramboasolo A, Rasolonavalona T, Raharisolo C, Rakotoaritahina H, Chanteau S, Boisier P
Direction des Services Vétérinaires, Ampandrianomby, Antananarivo, Madagascar.
Onderstepoort J Vet Res. 2001 Sep;68(3):231-8.
A sample survey with the objective of determining the prevalence of bovine tuberculosis by means of an intradermal tuberculin test was conducted in Madagascar and it was found that the prevalence rate varied from 0-30% by veterinary district. In order to estimate the true prevalence, the validity of the test was investigated by assessing its sensitivity and specificity in two groups of animals from two different regions, which were destined for slaughter. In the first group where the probability of non-infected animals should have been the highest, sensitivity was estimated at 0.52 (n = 21) and specificity at 0.99 (n = 79). In the second group selected on the basis of apparent ill health of the animals in a high-prevalence bovine tuberculosis area, sensitivity was estimated at 0.8 (n = 10) and specificity at 1 (n = 12). The results obtained from both groups of cattle were not combined for statistical purposes because the sensitivity of the skin test seemed to fluctuate in relation to the chronicity of the disease. These fluctuations are discussed. However, since the first group of zebu cattle was more representative of the cattle population across the country as a whole, its results were retained as operational parameters for further screening.
在马达加斯加开展了一项抽样调查，目的是通过皮内结核菌素试验确定牛结核病的流行率，结果发现按兽医管区划分，流行率在0%至30%之间。为了估计真实流行率，通过评估来自两个不同地区、即将被屠宰的两组动物的皮内结核菌素试验的敏感性和特异性，对该试验的有效性进行了调查。在第一组中，未感染动物的比例本应最高，估计敏感性为0.52（n = 21），特异性为0.99（n = 79）。在第二组中，是根据高流行率牛结核病地区动物明显健康状况不佳而挑选的，估计敏感性为0.8（n = 10），特异性为1（n = 12）。两组牛的结果未合并用于统计目的，因为皮试的敏感性似乎随疾病的慢性程度而波动。对这些波动进行了讨论。然而，由于第一组瘤牛更能代表全国的牛群总体情况，其结果被保留作为进一步筛查的操作参数。
