Dodson R F, Tagashira Y, Wai-Fong Chu L
J Neurol Sci. 1975 Oct;26(2):235-43. doi: 10.1016/0022-510x(75)90035-0.
Ultrastructural changes in cerebral tissue subjected to temporary occlusion on the right middle cerebral artery for intervals of 30 min, 1, 2, 3, and 4 hr were studied after daily injections of 10% glycerol in saline. These changes were compared with previously reported data from untreated animals. The extent of tissue involvement was appreciably less in the glycerol-treated group as evidenced by the reduction of intracellular edema and fewer changes in the membranes of ultrastructural elements (mitochondria, endoplasmic reticulum, Golgi complex, and plasmalemma) known to be essential for cellular metabolism and function in the central nervous system.
在每日注射10%甘油盐水后，研究了右侧大脑中动脉暂时闭塞30分钟、1小时、2小时、3小时和4小时的脑组织超微结构变化。将这些变化与先前报道的未治疗动物的数据进行比较。甘油治疗组的组织受累程度明显较轻，这表现为细胞内水肿减轻，以及对中枢神经系统细胞代谢和功能至关重要的超微结构成分（线粒体、内质网、高尔基体和质膜）的膜变化较少。
