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急性咽痛——全科医疗中的诊断与治疗

Acute sore throat--diagnosis and treatment in general practice.

出版信息

J R Coll Gen Pract. 1975 Feb;25(151):126-32.

Abstract

This study tested how general practitioners diagnose streptococcal infection on clinical grounds alone, in patients who presented with sore throats.Four hundred and fifty-two patients were admitted to the study. A clinical diagnosis, prognosis and follow-up was completed in each case and the clinical assessment was checked by throat swabbing at first contact and a week later.The doctors were inaccurate in predicting streptococcal infection, but better than might be expected if prediction were a matter of pure guesswork. Colds and influenza implied negative prediction, tonsillitis a positive prediction, and pharyngitis was doubtful.In this series negative prediction for pharyngitis was 85.2 per cent and positive prediction 31.5 per cent accurate. The equivalent figures for tonsillitis were 61.5 per cent and 38.9 per cent respectively. There was a general tendency to overpredict streptococcal infection which was most marked in acute follicular tonsillitis, but this led to few false negatives. The tendency to overpredict streptococci was most marked when the patient was an adolescent female.There were differences between the urban and rural patterns. During the same period, influenza (and similar illnesses) was recorded less often in the country, whereas urban practitioners were more likely to predict streptococcal infection. Rural practitioners were more accurate in prediction because they were less prone to implicate streptococcal infection than their urban colleagues; there was a higher proportion of cases with proven streptococcal infection in the town and there is a disproportionately high number of adolescent females among the urban patients.

摘要

本研究测试了全科医生仅基于临床症状对出现喉咙痛的患者进行链球菌感染诊断的情况。452名患者纳入本研究。对每个病例都进行了临床诊断、预后评估及随访,且在初次接触时和一周后通过咽拭子检查对临床评估进行核实。医生们在预测链球菌感染方面并不准确,但比纯粹凭猜测进行预测的预期情况要好。感冒和流感意味着阴性预测,扁桃体炎意味着阳性预测,而咽炎的预测结果存疑。在这个系列中,咽炎的阴性预测准确率为85.2%,阳性预测准确率为31.5%。扁桃体炎的相应数字分别为61.5%和38.9%。普遍存在过度预测链球菌感染的趋势,在急性滤泡性扁桃体炎中最为明显,但这导致的假阴性很少。当患者为青春期女性时,过度预测链球菌感染的趋势最为明显。城乡模式存在差异。在同一时期,农村地区记录到的流感(及类似疾病)病例较少,而城市医生更倾向于预测链球菌感染。农村医生的预测更准确,因为他们比城市同行更不容易将感染归咎于链球菌;城镇中经证实的链球菌感染病例比例更高,且城市患者中青春期女性的数量不成比例地高。

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