致癌霉菌毒素对依赖脱氧核糖核酸的核糖核酸聚合酶和核糖核酸酶H的抑制作用。
Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H.
作者信息
Tashiro F, Hiral K, Ueno Y
出版信息
Appl Environ Microbiol. 1979 Aug;38(2):191-6. doi: 10.1128/aem.38.2.191-196.1979.
Abstract
Fourteen mycotoxins were tested for inhibitory effects on ribonucleic acid polymerase of rat liver and Escherichia coli and nuclear ribonuclease H of rat liver and Tetrahymena pyriformis. These enzymes were strongly inhibited by (-)-luteoskyrin, (+)-rugulosin, patulin, and PR toxin.
摘要
检测了14种霉菌毒素对大鼠肝脏和大肠杆菌的核糖核酸聚合酶以及大鼠肝脏和梨形四膜虫的核糖核酸酶H的抑制作用。这些酶受到（-）-藤黄绿菌素、（+）-皱褶青霉素、展青霉素和PR毒素的强烈抑制。
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