Gautier M, Hayes H, Taourit S, Laurent P, Eggen A
Laboratoire de Génétique biochimique et de Cytogénétique, Département de Génétique Animale, INRA CRJ, Jou y-en-Josas, France.
Chromosome Res. 2001;9(8):617-21. doi: 10.1023/a:1012996005762.
A comparative mapping approach was applied in order to refine the extent and the distribution of conserved segments between the long arm of human chromosome 10 (HSA10) and cattle chromosomes 26 and 28 (BTA26 and BTA28 respectively). Sixteen genes localised on the long arm of HSA10 were mapped using a bovine-hamster somatic cell hybrid panel: twelve represent new assignments in cattle; the four others are in agreement with previous published data. This study confirms and refines the boundaries of the disruption zones between HSA10 and, BTA26 and BTA28, at the level of the human cytogenetic band.
为了细化人类10号染色体(HSA10)长臂与牛26号和28号染色体(分别为BTA26和BTA28)之间保守片段的范围和分布,采用了一种比较作图方法。利用牛-仓鼠体细胞杂种细胞系对位于HSA10长臂上的16个基因进行了定位:其中12个代表在牛中的新定位;另外4个与先前发表的数据一致。本研究在人类细胞遗传学带水平上证实并细化了HSA10与BTA26和BTA28之间断裂区域的边界。