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液体试验餐后人体小肠内容物的脂肪酶和辅脂肪酶活性。

Lipase and co-lipase activities of human small intestinal contents after a liquid test meal.

作者信息

Brogström B, Hildebrand H

出版信息

Scand J Gastroenterol. 1975;10(6):585-91.

PMID:1179151
Abstract

Methods for the determination of pancreatic lipase in small intestinal content have been re-evaluated in the light of the presence of co-lipase therein. A method is described for the determination of co-lipase in intestinal content based on its property to reactivate bile-salt-inhibited lipase. Figures are given for lipase and co-lipase activities in intestinal contents of normal humans aged 1-22. These two components originating in the pancreatic juice vary in a parallel fashion, and no variations with age were apparent. A simple diagnostic criterion is given to detect a possible specific co-lipase deficiency.

摘要

鉴于小肠内容物中存在辅脂酶,对测定其中胰脂肪酶的方法进行了重新评估。本文描述了一种基于辅脂酶能使胆汁盐抑制的脂肪酶重新激活的特性来测定小肠内容物中辅脂酶的方法。给出了1至22岁正常人类小肠内容物中脂肪酶和辅脂酶活性的数据。这两种源自胰液的成分呈平行变化,且未发现随年龄有明显变化。给出了一个简单的诊断标准以检测可能存在的特异性辅脂酶缺乏症。

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1
Lipase and co-lipase activities of human small intestinal contents after a liquid test meal.液体试验餐后人体小肠内容物的脂肪酶和辅脂肪酶活性。
Scand J Gastroenterol. 1975;10(6):585-91.
2
Tributyrine as a substrate for determination of lipase activity of pancreatic juice and small intestinal content.
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Importance of bile in regulation of intraluminal proteolytic enzyme activities in the rat.胆汁在调节大鼠肠腔内蛋白水解酶活性中的重要性。
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[Relation between blood hydrolases and small-intestinal contents].[血液水解酶与小肠内容物之间的关系]
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[Exocrine pancreatic secretions in normal infants and children].[正常婴幼儿的胰腺外分泌]
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Decrease of lipase and esterase activities in intestinal contents of newborn infants during test meals.试餐期间新生儿肠内容物中脂肪酶和酯酶活性的降低。
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Large doses of zinc oxide increases the activity of hydrolases in rats.大剂量氧化锌可提高大鼠体内水解酶的活性。
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Origin and development of exocrine pancreatic insufficiency in experimental renal failure.实验性肾衰竭中胰腺外分泌功能不全的起源与发展
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7
In vitro studies on bile acid deconjugation and lipolysis inhibition by Giardia lamblia.贾第虫对胆汁酸去结合作用及脂肪分解抑制的体外研究
Dig Dis Sci. 1981 Aug;26(8):700-4. doi: 10.1007/BF01316858.
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Hydrolysis of human milk fat globules by pancreatic lipase: role of colipase, phospholipase A2, and bile salts.胰脂肪酶对人乳脂肪球的水解作用:辅脂酶、磷脂酶A2和胆汁盐的作用
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Hydrolysis of milk fat globules by pancreatic lipase. Role of colipase, phospholipase A2, and bile salts.胰脂肪酶对乳脂肪球的水解作用。辅脂酶、磷脂酶A2和胆汁盐的作用。
J Clin Invest. 1982 Jul;70(1):30-2. doi: 10.1172/jci110599.
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Isolated co-lipase deficiency in two brothers.两兄弟中孤立性共脂肪酶缺乏症。
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