巴豆（大戟科）中的二萜类及其他成分。

Diterpenes and other constituents from Croton draco (Euphorbiaceae).

作者信息

Murillo R M, Jakupovic J, Rivera J, Castro V H

机构信息

Escuela de Química and CIPRONA (Centro de Investigación de Productos Naturales), Universidad de Costa Rica, 2060, Costa Rica.

出版信息

Rev Biol Trop. 2001 Mar;49(1):259-64.

PMID:11795154

Abstract

Croton draco (Euphorbiaceae) from Guadalupe, San José, Costa Rica was collected in July 1992 and phytochemically studied (leaves, seeds, wood, bark, sap and flowers separately). Commonly known compounds such as 1-hydroxyjunenol, p-hydroxybenzaldehyde, p-methoxybenzoic acid, 3,4,5-trimethoxycinnamyl alcohol, the coumarin scopoletin, the nor-terpenoids 9-dehydrovomifoliol and 2,3-dihydrovomifoliol were obtained. Taspine, two aporphinic alkaloids, the diterpenes 9(11)-dehydrokaurenic acid, hardwikiic acid, the corresponding new 12-oxo derivative as well as five clerodanes and a phorbol ester were also isolated. Three clerodanes were not previously described and their NMR spectroscopical data and MS fragmentation patterns are reported.

摘要

1992年7月，从哥斯达黎加圣何塞瓜达卢佩采集了巴豆属植物（大戟科），并对其进行了植物化学研究（分别研究叶子、种子、木材、树皮、树液和花朵）。获得了常见的化合物，如1-羟基朱诺醇、对羟基苯甲醛、对甲氧基苯甲酸、3,4,5-三甲氧基肉桂醇、香豆素东莨菪素、去甲萜类化合物9-脱氢米佛利醇和2,3-二氢米佛利醇。还分离出了塔斯平、两种阿朴菲生物碱、二萜类化合物9(11)-脱氢贝壳杉酸、硬维基酸、相应的新12-氧代衍生物以及五种克罗烷和一种佛波酯。三种克罗烷以前未被描述过，本文报道了它们的核磁共振光谱数据和质谱裂解模式。