Domres B, Gruenagel H H, Zittel R X
Acta Hepatogastroenterol (Stuttg). 1975 Aug;22(4):215-21.
The intraperitoneal injection of methyl cellulose in rats causes splenomegaly and hypersplenism. Clusters of foam cells in form of granulomas develop. They are containing methyl cellulose. The ligature of the splenic artery damages mainly the white pulp. Even after ligature of the splenic artery absorption of methyl cellulose continues. The reticular cells released by the reticulum remain capable of phagocytic action. After previous injection of methyl cellulose the ligature of the splenic artery causes normalization of the peripheral blood values.
给大鼠腹腔注射甲基纤维素会导致脾肿大和脾功能亢进。会形成肉芽肿形式的泡沫细胞簇。这些细胞簇含有甲基纤维素。结扎脾动脉主要损伤白髓。即使结扎脾动脉后，甲基纤维素的吸收仍在继续。网状组织释放的网状细胞仍具有吞噬作用。预先注射甲基纤维素后，结扎脾动脉可使外周血值恢复正常。
