Witte C L, Corrigan J J, Witte M H, O'Mara R E
Surgery. 1976 Nov;80(5):581-5.
The effects of splenic artery ligation (SAL) were examined in Sprague-Dawley rats with methyl-cellulose-induced hypersplenism. When performed close to the splenic hilium, SAL effectively reduced functioning splenic mass and raised peripheral counts of leukocytes and platelets, a response similar to that following total splenectomy. In hypersplenism, therefore, a satisfactory hematologic response may not necessary require total ablation of the spleen but merely substantial reduction of functioning splenic tissue.
在甲基纤维素诱导的脾功能亢进的Sprague-Dawley大鼠中研究了脾动脉结扎（SAL）的效果。当在靠近脾门处进行时，SAL有效地减少了有功能的脾体积，并提高了外周血白细胞和血小板计数，这一反应与全脾切除术后相似。因此，在脾功能亢进中，令人满意的血液学反应可能不一定需要完全切除脾脏，而仅仅是大幅减少有功能的脾组织。
