Alm A
Acta Physiol Scand. 1975 Sep;95(1):60-5. doi: 10.1111/j.1748-1716.1975.tb10025.x.
15 mum and 35 mum radioactive microspheres, differently labelled, were used simultaneously for rCBF-determinations in monkeys. Flow values calculated from data for 35 mum spheres were 27 +/- 7 g/min per 100 g higher for grey matter and 10 +/- 3 g/min per 100 g lower for white matter than flow values calculated from 15 mum spheres, while both sphere sizes resulted in similar values for the choroid plexus. A large number of 35 mum spheres were trapped in extracerebral pial arterioles. It is concluded that entrpment in relatively large arterioles of the 35 mum spheres explains the differences in flow values, and that this invalidates the use of 35 mum spheres, and larger, in rCBF-determinations.
15微米和35微米的放射性微球，标记不同，同时用于测定猴子的局部脑血流量（rCBF）。根据35微米微球数据计算出的血流量值，灰质比根据15微米微球计算出的血流量值每100克高27±7克/分钟，白质则低10±3克/分钟，而两种微球大小对脉络丛得出的数值相似。大量35微米的微球被困在脑外软脑膜小动脉中。得出的结论是，35微米微球被困在相对较大的动脉中解释了血流量值的差异，这使得在rCBF测定中使用35微米及更大尺寸的微球无效。
