Sonnenbichler J, Pohl A
Hoppe Seylers Z Physiol Chem. 1980 Nov;361(11):1757-61.
In order to find out those structural elements of the flavonolignane silybin which are essential for its stimulatory effect on RNA synthesis, a series of flavonoids etc. has been tested for efficiency. Isolated liver cell nuclei in vitro and hepatocyte cultures have been used to follow RNA synthesis. Only a few compounds show effects similar to those of silybin. Possible structural parameters essential for stimulation are discussed.
为了找出黄酮木脂素水飞蓟宾中对其刺激RNA合成效应至关重要的结构元素，已对一系列黄酮类化合物等进行了有效性测试。已使用体外分离的肝细胞核和肝细胞培养物来跟踪RNA合成。只有少数化合物显示出与水飞蓟宾类似的效果。讨论了刺激所必需的可能结构参数。
