鸡视网膜对谷氨酸的摄取
Glutamate uptake by chick retina.
作者信息
Tunnicliff G
出版信息
Biochem J. 1975 Aug;150(2):297-9. doi: 10.1042/bj1500297.
Abstract
The uptake of glutamate was found to be via a single high-affinity transport mechanism with Km values of 35 and 95 mum for chick-embryo and mature chick retina respectively. These data contrast with the uptake of gamma-aminobutyratewhich in the same tissue has previously been shown to display two kinetically distinct mechanisms in the embryo, but a single low-affinity process in the mature retina.
摘要
研究发现，谷氨酸的摄取是通过单一的高亲和力转运机制进行的，鸡胚视网膜和成熟鸡视网膜的米氏常数（Km值）分别为35和95微摩尔。这些数据与γ-氨基丁酸的摄取情况形成对比，此前已表明，在同一组织中，γ-氨基丁酸在胚胎期有两种动力学上不同的机制，但在成熟视网膜中是单一的低亲和力过程。
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本文引用的文献
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Transport systems for GABA and for other amino acids in incubated chick brain tissue during development.发育过程中孵育的鸡脑组织中γ-氨基丁酸及其他氨基酸的转运系统
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Postnatal changes in the high affinity uptake of glycine and GABA in the rat central nervous system.大鼠中枢神经系统中甘氨酸和γ-氨基丁酸高亲和力摄取的产后变化。
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