Tuchinda Patoomratana, Reutrakul Vichai, Claeson Per, Pongprayoon Ubonwan, Sematong Tuanta, Santisuk Thawatchai, Taylor Walter C
Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand.
Phytochemistry. 2002 Jan;59(2):169-73. doi: 10.1016/s0031-9422(01)00451-4.
The cyclohexenyl chalcone derivative [(-)-hydroxypanduratin A], together with the previously known panduratin A, sakuranetin, pinostrobin, pinocembrin, and dihydro-5,6-dehydrokawain were isolated from the chloroform extract of the red rhizome variety of Boesenbergia pandurata (Robx.) Schltr. [currently known as Boesenbergia rotunda (L.) Mansf., Kulturpfl.]. Their structures were assigned on the basis of their spectroscopic data. (-)-Hydroxypanduratin A and (-)-panduratin A showed significant topical anti-inflammatory activity in the assay of TPA-induced ear edema in rats.
从圆叶山奈（Boesenbergia pandurata (Robx.) Schltr. [现名为Boesenbergia rotunda (L.) Mansf., Kulturpfl.]）红根茎变种的氯仿提取物中分离出环己烯基查尔酮衍生物[(-)-羟基盘状菌素A]，以及先前已知的盘状菌素A、樱花素、豆甾醇、松属素和二氢-5,6-脱氢卡瓦因。根据它们的光谱数据确定了其结构。(-)-羟基盘状菌素A和(-)-盘状菌素A在大鼠TPA诱导的耳部水肿试验中显示出显著的局部抗炎活性。
