Nonomura Y, Miyamoto K, Wada E, Hosoe H, Nishimoto H, Ogura H, Shimizu K
Department of Orthopaedic Surgery, Gifu University School of Medicine, Gifu, Japan.
Spinal Cord. 2002 Jan;40(1):40-3. doi: 10.1038/sj.sc.3101247.
Two case reports of intramedullary teratoma in the spinal cord of adults, and a review of the literature.
To investigate and describe unusual cases of spinal teratoma using MRI to define features that may be used to avoid misdiagnosis.
A department of orthopedic surgery in Japan.
One patient, a 37-year-old woman, was referred because of gait disturbance. She was evaluated by myelography, CT scan with myelography, and MRI. T12 through L1 laminoplasty was performed and the tumor was subtotally removed. The other patient, a 56-year-old man, was referred because of muscle weakness and sensory disturbance. MRI revealed multiple spinal tumors. C4 through C6 laminoplasty and T12 through L2 laminoplasty were performed, and the tumors in these regions were subtotally removed.
In Case 1, the postoperative course was excellent, and histological examination of the resected specimen revealed a spinal teratoma consisting of ectodermal and mesodermal elements. In Case 2, the symptoms were resolved after surgery, and ectodermal, mesodermal and endodermal elements were revealed.
Although intramedullary teratomas are very rare in adults, they need to be considered in differential diagnosis.
两例成人脊髓髓内畸胎瘤的病例报告及文献综述。
利用磁共振成像（MRI）研究并描述脊髓畸胎瘤的罕见病例，以明确可用于避免误诊的特征。
日本某骨科手术科室。
一名37岁女性患者因步态障碍前来就诊。对其进行了脊髓造影、脊髓造影CT扫描及MRI检查。实施了T12至L1椎板成形术，肿瘤大部分切除。另一名56岁男性患者因肌肉无力和感觉障碍前来就诊。MRI显示多个脊髓肿瘤。实施了C4至C6椎板成形术及T12至L2椎板成形术，这些部位的肿瘤大部分切除。
病例1术后恢复良好，切除标本的组织学检查显示为包含外胚层和中胚层成分的脊髓畸胎瘤。病例2术后症状缓解，显示有外胚层、中胚层和内胚层成分。
尽管成人脊髓髓内畸胎瘤非常罕见，但在鉴别诊断时仍需考虑。
